A serious disease of nerve cells

A serious disease of nerve cells

A serious disease of nerve cells

There are many people especially old age that one may see with shaking hands which his nothing but a disease called as Parkinson. Parkinson’s disease tends to be a neurodegenerative disorder that gives rise to the progressive decline of motor function because of loss of dopamine -forming cells of the brain. The real cause of Parkinson’s disease remains unknown. However, researchers think that it is both environmental as well as genetic factors that are responsible for this disease. Several genes have been associated with this disease.

In primary symptoms are found as:

  • Tremor
  • Slowness
  • Stiffness
  • Impairment of balance
  • Afterward shuffling gait

In secondary symptoms are found as:

  • Anxiety
  • Depression
  • Then sets in dementia

Parkinson’s disease can be said to be a condition which has prime features as:

  • Slowness of movement
  • Tremors
  • Balance issues while walking or gait

Millions of people are faced with this disease all through the globe. This disease can occur in people in their 20s, but usually, it occurs to people at the age of sixty or more.

Cause of Parkinson’s disease

Parkinson’s disease sets in due to loss of nerve cells within a particular portion of the patient’s brain that is known as the substantia nigra. Cells found within substantia nigra correspond with various movement control centers within the brain by producing dopamine along with various neurotransmitters. As the death of the cells of substantia nigra happens, they discontinue secretion of dopamine, consequently, various movement control centers turn to be unregulated. This disturbance caused to the movement control centers present in the brain give rise to prime symptoms of Parkinson’s disease such as gait issues, sluggishness, and tremors.

In a number of patients, what is the cause of the loss of cells of substantia nigra is not known. Environmental toxins responsible for causing Parkinson’s disease are

  • Organic solvents 
  • Carbon monoxide 
  • Manganese 

 A certain type of pesticides 

A lot of people who have Parkinson’s disease had no exposure to these toxins. Several genes have been indicated to trigger this Parkinson’s disease nearly in 10% of patients. But such abnormalities have not been found to exist in most people who have Parkinson’s disease. At present researchers think that the cause of this disorder in most people can be the blend of environmental exposures and genetic factors. parkinson treatment in india is done with the existing line of treatment. 

Usual course or symptoms of Parkinson’s disease 

The first and foremost sign and disorder course differ significantly in individuals who have Parkinson’s disease. But some universal statements may be put forth, and very widespread starting symptom remains tremor. Symptoms of slowness and tremor generally start on one side of the patient’s body; it may involve either leg or arm. In due course of time within five years in some cases, the other extremity on the similar side and after that extremities or limbs found on the other side also get affected. Mobility, like walking or arising from any chair, shall be restricted with the progression of the disease. In the case of the most patients, there is not any effect on lifespan.

 

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